By Alice Dembner
GLOBE STAFF
A century after Alois Alzheimer identifi ed the
debilitating dementia that carries his name, scientists
are still trying to determine what causes the
disease in old age. Their quest takes on increasing
urgency, with predictions that unless a cure is found,
the number of Americans with the disease will rise
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Many scientists believe that Alzheimer’s results
from a complex interplay of environmental factors,
lifestyle choices, and genes and proteins gone haywire.
But the changes in the brain that characterize
the disease develop over decades and also occur in
some healthy seniors, making it diffi cult to sort out
the culprits from the bystanders.